What the Wells DVT score does
The Wells score for deep vein thrombosis is a clinical prediction rule that turns bedside findings into an estimated pre-test probability of DVT. By stratifying patients before any blood test or scan, it allows clinicians to use D-dimer testing and compression ultrasound efficiently and safely, avoiding unnecessary imaging in low-risk patients while ensuring high-risk patients are investigated promptly.
Scoring each criterion
Each of the following clinical features scores +1:
| Criterion | Notes on assessment |
|---|---|
| Active cancer | On treatment within 6 months, or palliative |
| Paralysis, paresis, or recent plaster immobilisation | Applies to the lower limb |
| Recently bedridden ≥3 days, or major surgery within 12 weeks requiring anaesthesia | Either criterion qualifies |
| Localised tenderness along the deep venous system | Femoral and/or popliteal |
| Entire leg swollen | Not just the calf |
| Calf swelling >3 cm compared to asymptomatic leg | Measured 10 cm below the tibial tuberosity |
| Pitting oedema confined to symptomatic leg | Not bilateral |
| Collateral superficial (non-varicose) veins | Present on examination |
| Previously documented DVT | Objectively confirmed |
One feature scores −2:
| Criterion | Notes |
|---|---|
| Alternative diagnosis at least as likely as DVT | For example: cellulitis, ruptured Baker’s cyst, muscle tear, superficial thrombophlebitis |
Interpreting the total score
In the two-tier model (more commonly used in UK/NICE guidance):
| Score | Risk tier | Suggested pathway |
|---|---|---|
< 2 | DVT unlikely | Perform high-sensitivity D-dimer; if negative, DVT excluded |
≥ 2 | DVT likely | Proximal leg compression ultrasound regardless of D-dimer |
In the three-tier model:
| Score | Risk tier | Approximate DVT prevalence |
|---|---|---|
≤ 0 | Low | Roughly 5% |
1–2 | Moderate | Roughly 17% |
≥ 3 | High | Roughly 53% |
Worked example
A 68-year-old patient attends with a unilateral swollen right leg. On assessment: active cancer (treated 3 months ago, +1), entire leg swollen (+1), calf swelling of 4 cm vs the left leg (+1), pitting oedema in the right leg only (+1), and no alternative diagnosis as likely as DVT. Total score = 4.
This is DVT likely (two-tier) and high probability (three-tier). The appropriate next step is proximal leg compression ultrasound — a D-dimer result would not safely exclude DVT at this score and is not needed before imaging.
Now consider a 35-year-old with a mildly swollen right calf who has just returned from a long-haul flight. Examination finds only localised calf tenderness (+1), but the clinician considers cellulitis an equally likely diagnosis (−2). Total = −1 — DVT unlikely. A high-sensitivity D-dimer, if negative, can safely rule out DVT without ultrasound.
Important clinical context
The Wells DVT score is validated for outpatient assessment of suspected lower-limb DVT. It is not designed for:
- Upper-extremity DVT (separate criteria apply)
- Patients already on anticoagulation
- Recurrent DVT in the same limb (prior DVT has already been awarded +1, which may skew the score)
- Pregnant patients (higher baseline DVT risk requires adjusted assessment)
Always use the score alongside clinical judgement and your local DVT pathway. In the UK, NICE NG158 recommends the two-tier Wells score combined with whole-leg ultrasound in the DVT-likely group. In North America and elsewhere, local guidelines may differ. This tool supports — but does not replace — clinical decision-making.