The GFR-based CKD staging tool maps any estimated glomerular filtration rate (eGFR) to its KDIGO chronic kidney disease G-stage and surfaces the practical implications — how often to monitor, which drugs to adjust, and when to refer. It is built for GPs, nephrologists, and pharmacists.
How it works
KDIGO divides kidney function into six bands by eGFR in mL/min/1.73 m²:
| eGFR (mL/min/1.73 m²) | Stage | Description |
|---|---|---|
| 90 or above | G1 | Normal or high |
| 60–89 | G2 | Mildly decreased |
| 45–59 | G3a | Mildly to moderately decreased |
| 30–44 | G3b | Moderately to severely decreased |
| 15–29 | G4 | Severely decreased |
| Below 15 | G5 | Kidney failure |
Enter the eGFR and the tool returns the matching stage, highlights it in the reference table, and shows stage-specific clinical guidance.
Reading the result and acting on it
The guidance scales with severity:
G1 and G2: Unless a marker of kidney damage is present (albuminuria, haematuria, structural change), these stages do not constitute CKD. Management focuses on cardiovascular risk reduction, blood pressure control, and addressing reversible causes. Annual eGFR review is appropriate.
G3a: The stage where clinical attention typically begins in earnest. Review renally-cleared medications: metformin should be reviewed at G3a and reconsidered at G3b, DOACs need dose-adjustment checks, and gabapentinoids accumulate with lower clearance. Screen for anaemia of chronic kidney disease and mineral-bone disorder. Review frequency typically increases to every 6–12 months.
G3b: Tighter monitoring, more aggressive risk-factor control, and consideration of nephrology involvement for rapidly declining or complex cases. Ensure patients have had dietary advice appropriate to their stage.
G4: This stage typically triggers nephrology referral for preparation for renal replacement therapy (RRT) — whether transplant listing, fistula formation for haemodialysis, or peritoneal dialysis education. Even when not yet symptomatic, earlier referral means better-prepared patients and less emergency dialysis initiation.
G5: Kidney failure. If not on RRT or managed conservatively, urgent nephrology involvement is needed.
Why eGFR alone is not enough for G1 and G2
A single eGFR of 75 or 85 does not diagnose CKD by itself. KDIGO requires either:
- A persistently reduced eGFR (below 60) confirmed on two samples at least 90 days apart, or
- An eGFR of 60 or above plus a marker of kidney damage such as albuminuria (ACR above 3 mg/mmol), haematuria of renal origin, or an abnormality on imaging or biopsy.
This prevents over-diagnosing CKD in patients who have a transiently low eGFR (acute kidney injury, dehydration) or whose baseline is just below 90.
The albuminuria dimension
Full KDIGO staging combines the G-stage with an albuminuria category:
| ACR (mg/mmol) | Category | Description |
|---|---|---|
| Below 3 | A1 | Normal to mildly increased |
| 3–30 | A2 | Moderately increased |
| Above 30 | A3 | Severely increased |
Two patients at G3a can have dramatically different cardiovascular and renal prognosis depending on whether their ACR is A1 or A3. The combined G-and-A heat-map is the complete KDIGO risk classification. This tool handles the G-staging; the A-category adds an additional layer of risk stratification beyond the scope of eGFR alone.
Important caveats
All logic runs locally in your browser; nothing is sent to a server. This tool is for clinical reference and educational use — it does not replace clinical judgement, local guidelines, or individual patient assessment. eGFR equations (CKD-EPI 2021, MDRD) each have known limitations in extremes of muscle mass, age, and acute illness.