The Child-Pugh score, originally the Child-Turcotte-Pugh classification, grades the severity of chronic liver disease. It combines two laboratory measures of synthetic function, one of cholestasis, and two clinical signs of decompensation into a simple A, B, or C category that has guided prognosis and surgical decisions for decades.
How it works
Each of five parameters is scored 1, 2, or 3:
Bilirubin (mg/dL): <2 = 1 | 2-3 = 2 | >3 = 3
Albumin (g/dL): >3.5 = 1 | 2.8-3.5 = 2 | <2.8 = 3
INR: <1.7 = 1 | 1.7-2.3 = 2 | >2.3 = 3
Ascites: none = 1 | mild = 2 | moderate-severe = 3
Encephalopathy: none = 1 | grade 1-2 = 2 | grade 3-4 = 3
The five points are summed:
5-6 = Class A
7-9 = Class B
10-15 = Class C
Worked example
A patient with bilirubin 1.5 mg/dL (1 point), albumin 3.0 g/dL (2 points), INR 1.5 (1 point), mild ascites (2 points), and no encephalopathy (1 point) scores 7 total — Class B. They have compensated-to-borderline disease with meaningful functional compromise.
What each class means clinically
Class A (5–6 points): well-compensated
Patients in Child-Pugh A have near-normal synthetic function and no or minimal clinical decompensation. They can generally tolerate major surgery, including hepatic resection of lesions, provided the future remnant liver volume is adequate. Estimated one-year survival is roughly 95–100%.
Class B (7–9 points): significant functional compromise
Class B indicates important impairment of synthetic and excretory function, often with ascites that requires diuretics or paracentesis. Elective major surgery carries substantially elevated mortality risk; operative decisions require careful multidisciplinary review. Estimated one-year survival is around 80%.
Class C (10–15 points): decompensated disease
Class C represents advanced failure of hepatic reserve with severe coagulopathy, refractory ascites, and often recurrent encephalopathy. Elective major surgery is generally contraindicated. Class C patients should typically be evaluated for liver transplantation rather than hepatic resection. Estimated one-year survival is around 45%.
Child-Pugh versus MELD
Both scores predict mortality in cirrhosis, but they serve slightly different roles in clinical practice:
| Feature | Child-Pugh | MELD |
|---|---|---|
| Inputs | 3 labs + 2 clinical signs | 3 labs only (creatinine, bilirubin, INR) |
| Output | Category (A/B/C) | Continuous score |
| Subjectivity | Ascites and encephalopathy grading | Minimal |
| Primary use | Surgical risk, bedside staging | Transplant organ allocation |
Child-Pugh’s use of clinical signs introduces inter-observer variability, but it also captures information — ascites status and encephalopathy grade — that is directly relevant to perioperative risk. MELD, being entirely lab-based, is more reproducible but may miss some clinically relevant dimensions of decompensation. Most hepatology services use both rather than one or the other.
Documentation note
The two clinical inputs (ascites, encephalopathy) should be graded and documented at the time of the assessment, along with the basis for the grade (clinical examination, imaging, response to lactulose, etc.). This is important both for reproducibility and for medico-legal purposes when the score is used in surgical risk communication.